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CURRENT ISSUEGAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

A Journal on Internal Medicine and Pharmacology


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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2008 April;167(2):67-72

language: Italian

Advanced systemic sclerodermia complicated by acute respiratory distress

Russo A., Zaottini A.

Struttura Ospedaliera Complessa Pronto Soccorso Chirurgico Presidio Ospedaliero “Leopoldo Parodi Delfino”, Colleferro ASL Roma G, Roma


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Systemic sclerodermia is a rare autoimmune pathology, with a negative long term prognosis, not exceeding 10-year survey (20%). Preferably affecting females, (F:M =5:1), and adults (30-50 years of age), it generally arises from derma and cutaneous district, exhibiting an hyperproduction of collagenes, and spreading to all other organs. It causes vascular stenosis, especially arteriolar occlusion, damaging tissues (kidney, lung, heart). Bad life expectance is due to the absence of etiological therapy, which is still only symptomatic.

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