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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2008 April;167(2):67-72
Advanced systemic sclerodermia complicated by acute respiratory distress
Russo A., Zaottini A.
Struttura Ospedaliera Complessa Pronto Soccorso Chirurgico Presidio Ospedaliero “Leopoldo Parodi Delfino”, Colleferro ASL Roma G, Roma
Systemic sclerodermia is a rare autoimmune pathology, with a negative long term prognosis, not exceeding 10-year survey (20%). Preferably affecting females, (F:M =5:1), and adults (30-50 years of age), it generally arises from derma and cutaneous district, exhibiting an hyperproduction of collagenes, and spreading to all other organs. It causes vascular stenosis, especially arteriolar occlusion, damaging tissues (kidney, lung, heart). Bad life expectance is due to the absence of etiological therapy, which is still only symptomatic.