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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2007 April;166(2):81-4
Endometrial osseous metaplasia: case report
Bergante B., Croce P., Frigoli, Di Mario A. M.
Divisione di Ginecologia ed Ostetricia del Civico Ospedale di Codogno (LO)
Endometrial osseous metaplasia is a rare but benign condition resulting from endometrial ossification. Its pathogenesis is still unclear. The condition is associated with a history of spontaneous abortion, but it has also been reported in nulliparous women. While endometrial ossification may be occasionally revealed at echography in clinically asymptomatic patients, the clinical picture is often characterized by menometrorrhagia, pelvic pain and dysmenorrhea; an association with infertility has also been reported. Our patient presented with a vague clinical picture, recurrent episodes of abnormal uterine bleeding and a history of infertility. Echography disclosed typical features of endometrial ossification: a hyperechoic area with sharp, irregular borders and a posterior shadow above the uterine neck. At hysteroscopy the metaplastic area was revealed and removed with mechanical endoscopic instruments. The postoperative course was uneventful for abnormal bleeding. Postoperative estrogen therapy was not considered necessary.