Advanced Search

Home > Journals > Gazzetta Medica Italiana Archivio per le Scienze Mediche > Past Issues > Gazzetta Medica Italiana Archivio per le Scienze Mediche 2005 August;164(4) > Gazzetta Medica Italiana Archivio per le Scienze Mediche 2005 August;164(4):269-74

ISSUES AND ARTICLES   MOST READ

CURRENT ISSUEGAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

A Journal on Internal Medicine and Pharmacology

Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index

Frequency: Monthly

ISSN 0393-3660

Online ISSN 1827-1812

 

Gazzetta Medica Italiana Archivio per le Scienze Mediche 2005 August;164(4):269-74

    ORIGINAL ARTICLES

Increased adrenomedullin levels in nontraumatic septic patients

Guneysel O. 1, Ozturk T. 1, Umuroglu T. 2

1 Department of Emergency Medicine, Marmara University Faculty of Medicine, Uskudar/Istanbul, Turkey;
2 Department of Anesthesiology and Reanimation, Marmara University Faculty of Medicine, Uskudar/Istanbul, Turkey

Aim. The study objective was to assess plasma Adrenomedullin (ADM) levels in patients with nontraumatic sepsis. Also we investigated plasma ADM levels as a marker for early detection and evaluation of the severity of sepsis.
Methods. We measured plasma ADM levels in 49 nontraumatic various forms of septic patients and 42 healthy volunteers serving as controls.
Results. Plasma levels of ADM in patient group (150.38±99.60 fmol/ml) was significantly higher than that of controls (8.07±5.52 fmol/ml). In spite of the difference between the patient group and controls, no correlation was found between the severity of sepsis and plasma ADM levels. Also plasma ADM levels were not different between the sources of sepsis.
Conclusion. The plasma ADM levels are markedly increased in septic patients with different sources of infections, probably due to either decreased clearance or increased synthesis by the affected organs but the source of infection does not have an effect on this increase.

language: English


FULL TEXT  REPRINTS

top of page