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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2004 April;163(2):37-41

language: Italian

Intestinal microparasitosis in patients with HIV infection: personal experience

Pellicanò S. 1, Calzone R. 1, Bertuccio A. 2, Rombolà F. 2, Bertuccio S. N. 2

1 Divisione di Malattie Infettive, Ospedale «S. Giovanni di Dio», ASL n. 5, Crotone;
2 Divisione di Malattie Infettive, Ospedale «G. Jazzolino», ASL n. 8, Vibo Valentia, Regione Calabria


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Aim. In patients with HIV infection, diarrhea, often associated with getting thin and weight loss, is important for their nutritional state and quality of life, since these patients have a greater degree of immunosuppression than those without diarrhea, predisposing the gastrointestinal tract to the action of bacterial, viral, protozoa and fungal pathogens which may cause morbidity and death. These patients are particularly susceptible to protozoa infections. Cryptosporidium infection is among the most common causes of enteric disease but Micro-sporidium and Cyclospora are emerging as potentially important enteric pathogens.
Objective. The aim of this study was to evaluate diagnostic iter in intestinal microparasitosis in the light of the considerable dangerousness and aggressiveness of some protozoa. The methods for the diagnosis of intestinal microparasitosis are based particularly on direct diagnosis (macro or microscopic examination at fresh or after concentration) or an immunological diagnosis.
Results. The laboratory methods available at present permit to evidence different protozoa not evidenced in the past and without invasive techniques.
Conclusion. In spite of frequent involvement of the gastrointestinal tract, the knowledge of diarrhea syndromes AIDS-related are often greatly limited by diagnostic difficulties. The difficulty of diagnosis and therapy of intestinal pathogens is one of the greater problems in the management of HIV+ patients, since infection type and clinical answer are influenced by trasmission way, immunity state of the patient, geographic area and answer to therapy.

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