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A Journal on Internal Medicine and Pharmacology

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Gazzetta Medica Italiana Archivio per le Scienze Mediche 2003 June;162(2-3):55-66

language: Italian

Use of antibiotic in a hospital environment: the "Maddalena Raimondi" Hospital unit of San Cataldo (Caltanisetta)

Cimino V. 1, Medico L. 2, Seminatore G. F. 2

1 Scuola di Specializzazione in Farmacia Ospedaliera, Facoltà di Farmacia, Università degli Studi di Catania, Catania;
2 Ospedale «Maddalena Raimondi» di San Cataldo Azienda per i Servizi Sanitari 2, Caltanissetta


Aim. Generally speaking, antibiotics have a high average cost and their use represents a major percentage of hospital pharmaceutical expenditure. Their correct and appropriate deployment is therefore fundamental if hospital expenditure is to rationalised.
Methods. The present paper analyses the data relative to the consumption of antibiotics in 2001 in the Maddalena Raimondi Hospital Unit of San Cataldo (Caltanissetta). The data have been aggregated by antibiotic product and by hospital department.
Results. The departments that make most use antibiotics are Medicine and Surgery, followed by Orthopaedics. The most commonly used active principle is Ceftriaxone with which more than 1/4 of patients were treated and which representes the antibiotic of choiche in treatment. Cefonicid, Piperacillin and Netilmycin follow in the order of frequency.
Conclusion. From the available data it is not possible to make a cost effectiveness analysis but from the indications relative to the diagnosed pathologies it can be evinced that for therapeutic purposes the antibiotic of choice is Ceftriaxone whereas Cefonicid is preferred in surgical prophylaxis because of its low cost. The use of high cost antibiotics is limited to the most serious pathologies or where resistance to other products is suspected. Those active principles fo which a single daily administration is sufficient are, however, to be preferred. Ceftriaxone proves to be the most used antibiotic even if compared with the Airone study.

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