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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2002 October;161(4-5):185-91
Sevoflurane in the treatment of acute intraoperative bronchospasm
Polisca R., Romeo C., Cellini C.
We present a case of a young 9-year-old male patient, who developed acute onset of bronchospasm immediately after intubation. The course of severe asthma attack, unresponsive to maximum medical therapy by which improved in response to sevoflurane, suggests indications for this inhaled anaesthetic agent. The rapid decrease in bronchospasm and improvement in respiratory failure cannot be attributed to the effects of sevoflurane alone. However, the temporal relationship of their improvement to the administration of the inhaled anaesthetic suggest that sevofluorane substantially contributed to improvement. Indications for the use of inhaled anaesthetic agents for acute intraoperative bronchospasm are: 1) persistent hypoxia despite maximum aerosol and parental drug treatment and mechanical ventilation; 2) persistently high inspiratory airway pessures, particularly when associated with haemodynamic instability; 3) persistent life threatening air leak syndromes during mechanical ventilation.