Total amount: € 0,00
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1812
Niglio A. 1, Di Micco P. 1, Chirico G. 1, Di Giuseppe D. 1, Russo F. 1, De Vita F. 2, Torella R. 1
1 Department of Geriatrics, Gerontology and Metabolism Diseases, Division of General Medicine;
2 Division of Oncology, Second University of Naples, Naples, Italy
We report a case of deep vein thrombosis of the right leg occurring in a 56-year-old man with lung cancer. Deep vein thrombosis was treated with unfractioned heparine, but thrombophilia was persistent also after its therapy and was testified by high plasma rate of prothrombin 1+2 fragment (F1+2). Lung cancer was in local advanced stage (T3N0M0). Chemotherapy was performed with gemcitabine and carboplatinum for treatment of lung cancer. This case suggests that there is a thrombophilic state in natural history of the oncological disease and cancer is the most common acquired cause of thrombosis. Thrombosis can occur as an early or late sign of the disease, because many mechanisms are involved in cancer related vascular thrombosis.