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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2002 June;161(3):113-8
Electrocardiographic pattern of the global T wave inversion
Carrieri L., Paglia I., Morello M., Mangiardi L.
Dipartimento di Medicina Interna, Cattedra di Cardiologia, Università degli Studi di Torino, Torino
The global T wave inversion is a primary electrocardiographic modification that is present in many cardiac and non-cardiac diseases, in metabolic or electrolytic abnormalities and also in healthy subjects, as occasional finding. It’s more frequent in women, it’s not associated with coronary artery disease and it has a good prognosis. The case of a young woman admitted to the hospital because of feeling of “weight” on the chest, with global T wave inversion on ECG and normal coronary arteries, is presented. Several hypotheses were proposed to explain this kind of abnormality: the role of catecholamines, the electrical eterogenity in the ventricular wall, the alterations of potassium channels. Dobutamine stress echocardiography could be a first line test in order to exclude coronary artery disease, mostly in asymptomatic patients. A T wave normalization, associated with a normal basal echo, not modified by dobutamine infusion, could identify patients with non-ischemic ECG alteration.