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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 2001 December;160(6):199-203
Use of a preparation based on usnic acid and zinc sulphate in the treatment of vaginitis and bacterial vaginosis
Putricelli R., Zito M., Guatta Cescone P., Bongiolatti M.
Azienda Ospedaliera «S. Antonio Abate», Gallarate - Milano, Unità Operativa di Ostetricia e Ginecologia
Background. The aim of this study was to evaluate the efficacy of a product based on zinc sulphate in association with usnic acid in the treatment of vaginitis and bacterial vaginosis.
Methods. The study included a total of 20 patients of child-bearing age, ranging between 18 and 50 years old, who were sexually active with a diagnosis of bacterial vaginitis based on vaginal swab tests. The study prescribed treatment with usnic acid and zinc sulphate in ovules (Zeta N, Bergamon Italy): one ovule a day on alternate days for 10 days. Compliance was assessed using a multiple question sheet compiled by the patient.
Results. There was a full resolution of all cases (no. 16) of Gardnerella vaginalis and mixed bacterial infections. In cases of bacterial injection associated with Candida albicans (3 cases), there were 2 cases of complete remission. No resolution was achieved in the only case of bacterial infection associated with Trichomonas.
Conclusions. In conclusion, treatment with Zeta N was effective, above all in the treatment of bacterial forms not associated with mycetes or protozoa.