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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 December;158(6):175-80
Colour Duplex Ultrasonography tested in vascular penile disfunction. Incidence on atherosclerotic population and therapeutic perspectives in microcirculation
Carini U., Manusia F.
EO «Misericordia» - USL n. 9 - Grosseto, UO Malattie Cardio-Vascolari, Modulo di Angiologia Medica e Diagnostica Vascolare
Background. The real incidence of vasculogenic impotence in unknown. Colour duplex ultrasonography with erection induced drug tests (PGE1) is one of the most accurate patterns on reproducibility of penile arterial circulation. Power duplex and echo enhancing agents can permit to study low resistance arterioles and to find the second or third order of branches.
Methods. Through the symptom of “impotence” (inquired with Erectile Disfunction International Index-EDII), 75 subjects on atherosclerotic population of our cardio-vascular Laboratory have been selected; abnormal echo-therapy test for vascular damage have been found in 77%, with a global reduction in arteriolar bed. The patients were enrolled in an open study and subdivided into two groups to undergo therapy for six months with Pentoxi-fylline 600 mg and /or Ginkgo biloba-Mg-L arginine agents.
Results. Symptoms (number and frequency of erection EDII-like) and stress Echo were increased in 78% of treated patients with Ginkgo biloba against 49% of the othe group.
Conclusion. The study confirms the role of penile microcirculation in vascular impotence mechanism; like in other districts, the treatment with the described vegetable agents seem to be able to improve small vessels and to be effective in the management of erectile dysfunction, so frequent in patients with atherosclerotic cardio vascular disease.