Home > Journals > Gazzetta Medica Italiana Archivio per le Scienze Mediche > Past Issues > Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 October;158(5) > Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 October;158(5):169-73

CURRENT ISSUE
 

ARTICLE TOOLS

Reprints

GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

A Journal on Internal Medicine and Pharmacology


Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index

 

CLINICAL CASES  


Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 October;158(5):169-73

language: English

Toxoplasmosis and ur­ti­car­ia

Barbosa Vosgerau J. C.

Dermalogist, Centro Municipal de Especialidades, Secretary of Health ­from Ponta Grossa (Brasil)


PDF  


Chronic ur­ti­car­ia sev­e­ri­ty may be ­linked not on­ly to se­vere prur­it­us but al­so to life­threat­en­ing con­di­tions, as Quinck’s ede­ma or anaph­y­lac­tic ­shock. There of­ten is too ­poor a re­sponse to ­anti-his­ta­min­ics or cor­ti­cos­ter­oids. Even ­these med­i­cines can trig­ger ur­ti­car­ia or anaph­y­lac­tic ­shock. Chronic tox­o­plas­mo­sis is rare­ly re­mem­bered in pa­ti­ens ­with ur­ti­car­ia. Toxoplasmosis symp­toms are non-spe­cif­ic. Four pa­tients are re­port­ed ­with se­vere chron­ic ur­ti­car­ia, un­re­spon­sive to the usu­al meas­ures, ­long-stand­ing for ­between 2-42 ­years, and tox­o­plas­mo­sis ­that had anaph­y­lac­tic ­shock to I.V. hy­dro­cor­ti­sone, Quinck’s ede­ma, lip ede­ma, asth­ma, nau­sea, head­ache, ar­thritis/ar­thral­gia, uri­nary in­fec­tion, ­heart dis­or­ders, ­that ­were treat­ed ­with spe­cif­ic tox­o­plas­mo­sis med­i­cines (rox­ith­rom­y­cin, dap­sone, py­ri­meth­a­mine) and ­there was re­mis­sion of ur­ti­car­ia and ­these oth­ers com­plaints. It is pos­tu­lat­ed ­that se­vere ur­ti­car­ia may be ­just a vis­ible con­se­quence of the cy­to­kine ­storm trig­gered by Toxoplasma in the ­host and cer­tain­ly IFN-γ and TNF-α ­have a cen­tral ­role in the pa­thoph­y­sio­lo­gy of ­this ­skin dis­ease be­yond the oth­er re­port­ed dis­or­ders.

top of page

Publication History

Cite this article as

Corresponding author e-mail