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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 August;158(4):117-20
Toxoplasmosis and neurotic excoriations
Barbosa Vosgerau J. C.
Private Clinic, Ponta Grossa - Pr, Brasil
Neurotic excoriation is considered a dermatological expression of a psychiatric disorder that usually responds poorly to psychiatric drugs. However, toxoplasmosis complaints are protean and non-specific. Irritabilility is a usual complaint in patients with chronic toxoplasmosis. Two 2 patients are presented, suffering from severe irritability, arthralgia/arthritis, bone pain, severe headache, memory deterioration, blurred vision, urinary infections, alopecia, herpes simple (HS), urticaria, one of them with asymptomatic DM type 2. The use of specific medicines to toxoplasmosis was concomitant with remission of irritability and neurotic excoriations, even glycemia normalization, in spite of pregnancy. The interruption of the specific medicines in one of them was accompanied by progressive symptoms relapse. It is postulated that such irritability may be related to IFN-γ, and particularly to IFN-α host “intoxication”, triggered by toxoplasma.