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CURRENT ISSUEGAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE

A Journal on Internal Medicine and Pharmacology


Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index

 

Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 August;158(4):117-20

 CLINICAL CASES

Toxoplasmosis and neu­ro­tic ex­co­ri­a­tions

Barbosa Vosgerau J. C.

Private Clinic, Ponta Grossa - Pr, Brasil

Neurotic ex­co­ri­a­tion is con­sid­ered a der­mat­o­log­i­cal ex­pres­sion of a psy­chi­at­ric dis­or­der ­that usu­al­ly re­sponds poor­ly to psy­chi­at­ric ­drugs. However, tox­o­plas­mo­sis com­plaints are pro­te­an and non-spe­cif­ic. Irritabilility is a usu­al com­plaint in pa­tients ­with chron­ic tox­o­plas­mo­sis. Two 2 pa­tients are pre­sent­ed, suf­fer­ing ­from se­vere ir­ri­ta­bil­ity, ar­thral­gia/ar­thritis, ­bone ­pain, se­vere head­ache, mem­o­ry de­te­ri­ora­tion, ­blurred vi­sion, uri­nary in­fec­tions, al­o­pe­cia, ­herpes sim­ple (HS), ur­ti­car­ia, one of ­them ­with asymp­to­mat­ic DM ­type 2. The use of spe­cif­ic med­i­cines to tox­o­plas­mo­sis was con­com­i­tant ­with re­mis­sion of ir­ri­ta­bil­ity and neu­ro­tic ex­co­ri­a­tions, ­even gly­ce­mia nor­mal­iza­tion, in ­spite of preg­nan­cy. The inter­rup­tion of the spe­cif­ic med­i­cines in one of ­them was ac­com­pa­nied by pro­gres­sive symp­toms re­laps­e. It is pos­tu­lat­ed ­that ­such ir­ri­ta­bil­ity may be re­lat­ed to IFN-γ, and par­tic­u­lar­ly to IFN-α ­host “in­tox­i­ca­tion”, trig­gered by toxoplasma.

language: English


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