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GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE
A Journal on Internal Medicine and Pharmacology
Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Gazzetta Medica Italiana Archivio per le Scienze Mediche 1999 June;158(3):95-9
The use of transcutaneous FANS in the treatment of superficial phlebitis
Dal Ry D., Contessa L., Tridico F., Capalbo M. T., Rosa R., Caldart M., Brachet R., Rebecchi F., Panier Suffat P.
Università degli Studi - Torino, Istituto di Clinica Chirurgica Generale e Terapia Chirurgica
The aim of the authors was to evaluate a new FANS administration method: the LAT system (Local Action Transcutaneous) in the vascular field, and more precisely in a typical phlogistic pathology of the venous trunk: superficial phlebitis.
The studies reported in the literature confirm the authors choice of “Flurbiprofen LAT”. The results of several studies on phlogistic pathologies of an orthopedic nature show that this transcutaneous preparation can determine constant therapeutic concentrations of the active ingredient in the application site, whithout any systemic activity, thus avoiding the systemic collateral effects typical of FANS. The authors, evaluated the local analgesic and anti-inflammatory activity, also analysing the time taken for typical signs of phlogosis to disappear. Moreover, the collateral effects and acceptability of the new formulation by patients were also examined. The results obtained are valid both in terms of efficacy and rapidity. In view of the virtual absence of collateral effects and the high acceptability of this new formulation by patients, the authors recommend its extensive use in the treatment of superficial phlebitis.