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Indexed/Abstracted in: BIOSIS Previews, EMBASE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1812
Zarcone R., Carfora E., Bellini P., Tartaglia E., Tomasillo G., Longo M.
2nd University of Naples, Department of Obstetrics and Gynecology
Background. The aim of the present study was to evaluate the effectiveness of the natural methods for fertility control. Moreover we evaluated the practicality and all the other characteristics of each of these methods.
Methods. Between January 1994 and September 1995 we have studied at the Obstetric and Gynecologic Clinic of the 2nd University of Naples, 15 females, aged 24-42. We studied the vulvar wetness sensation method and the ferning test. We tested the validity of the determination of the fertile period by the luminescent immunoassay laboratory technique to determinate the levels of oestrone-3 glucuronide and pregnandiol 3-glucuronide in the urine.
Finally we determined the level of beta-glucuronidase in saliva.
Results. Quantitative determination of the cervical mucus: the amount of the cervicovaginal fluid which is accumulated in the upper vagina and in the posterior fornix can be related to the preovulatory and ovulatory stages of the cycle. In 38% of the cases, wetness was felt during the three days preceding ovulation, in 26% on the day of ovulation, and in 36% during the 4 days following ovulation.
Determination of hormone levels: the oestrone and pregnandiol levels, in different women, can be correlated with one another, but they are remarkably different both in the mean values and the peaks of these hormones in the urine.
Saliva enzymatic levels: a major variability in the width of beta-glucuronidasi peak was observed, probably related to the length of the fertile period.
Conclusions. It is suggested to improve the preparation of colorimetric kit based on determination of urine hormone levels to establish the fertile period in a natural way.