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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1642
PANCREATIC DISEASES: A CLOSER LOOK
Easler J. J., Mounzer R., Papachristou G. I.
Division of Gastroenterology,, Hepatology and Nutrition, University of Pittsburgh Medi cal Center, Pittsburgh, PA, USA
Acute pancreatitis is a disease of variable severity that can lead to significant morbidity and mortality. Current management has remained limited to supportive measures and the treatment of complications. A myriad of pharmacologic therapies targeting various aspects of the underlying pathophysiology have been evaluated over the past few decades. These have included antisecretory agents, protease inhibitors, antioxidants, immunomodulators, non-steroidal anti-inflammatory medications, and prophylactic antibiotics. A few of these therapies have demonstrated promise in significantly altering the progression of this disease. Further studies are needed to clearly elucidate these benefits in patients at risk for poor outcomes