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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1642
ADVANCES IN INFLAMMATORY BOWEL DISEASES
Li Y. 1, 2, Zhu H. 2, Shen B. 2
1 Department of Gastroenterology, Peking Union Medical College Hospital, Beijing, China;
2 Department of Gastroenterology/Hepatology, The Cleveland Clinic Foundation, Cleveland, OH, USA
Approximately 20-30% of patients with ulcerative colitis would eventually require surgery despite recent advances in medical therapy. Ileal pouch-anal anastomosis has become the surgical treatment of choice after total proctocolectomy. A subset of patients who had a preoperative diagnosis of ulcerative colitis may develop Crohn’s disease or a Crohn’s disease-like condition of the ileal pouch after surgery. Diagnosis, differential diagnosis, and management of Crohn’s disease of the ileal pouch have been challenging. A combined approach with the assessment of clinical history, endoscopy, histology, abdominal/pelvic imaging, and examination under anesthesia is necessary for an accurate diagnosis, disease classification, management and improvement in outcome. A multidisciplinary approach with gastroenterologists, colorectal surgeons, gastrointestinal pathologists and radiologists for proper medical, endoscopic, and surgical treatment is advocated.