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Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Online ISSN 1827-1642
PERIOPERATIVE CARE IN LIVER TRANSPLANTATION
Assis D.N., Schilsky M.L.
Section of Digestive Disease and Section of Transplantation and Immunology Yale University School of Medicine
New Haven, CT, USA
Caring for patients with advanced liver disease and acute liver failure requires a thorough understanding of the profound coagulation changes that occur in these conditions. Due to the unique nature of the pathophysiologic changes from hepatic dysfunction, effective interpretation and management of coagulopathy and thrombocytopenia with blood products are important clinical skills, and are likewise required in the post transplant period. Acute superimposed complications such as sepsis and renal dysfunction present additional challenges. The aim of this review was to describe the coagulation changes in liver disease, appropriate coagulation testing, and management strategies in the pre- and post-transplant period.