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MINERVA GASTROENTEROLOGICA E DIETOLOGICA
A Journal on Gastroenterology, Nutrition and Dietetics
Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
CASE REPORTS CLINICAL ADVANCES IN INFLAMMATORY BOWEL DISEASE
Minerva Gastroenterologica e Dietologica 2007 September;53(3):279-83
Hepatocellular carcinoma complicating primary sclerosing cholangitis in Crohn’s disease. A case report
Demarchi B., Bresso F., Novero D., Palestro G., Sapone N., Pellicano R., Bonardi R., Smedile A., Rizzetto M., Astegiano M.
1 Department of Gastroenterology Molinette Hospital, Turin, Italy
2 Institutionen for Medicin Karolinska Institutet, Stockholm, Sweden
3 Department of Biomedical Sciences and Human Oncology University of Turin, Turin, Italy
The prevalence of primary sclerosing cholangitis (PSC) in Crohn’s disease (CD) patients is up to 8.5%. Although cholangiocarcinoma may complicate long-standing PSC in one third of the cases if follow-up is extended long enough, hepatocellular carcinoma (HCC) is a rare complication of PSC. The concomitant presence of PSC, HCC and CD have been reported sporadically. We discuss here a case of association of these three conditions.