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MINERVA GASTROENTEROLOGICA E DIETOLOGICA
A Journal on Gastroenterology, Nutrition and Dietetics
Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
REVIEWS CLINICAL ADVANCES IN GERD
Minerva Gastroenterologica e Dietologica 2007 June;53(2):171-80
Gastroesophageal reflux and its possible role in the pathogenesis of upper aerodigestive tract disorders
Ciorba A., Bianchini C., Pelucchi S., Pastore A.
Otolaryngology Department University Hospital of Ferrara, Ferrara, Italy
Associations have been reported between gastroesophageal reflux (GER) and a variety of upper and lower respiratory tract conditions. Respiratory conditions and GER are common and would be expected to coexist in many patients. Whether there is a relationship between GER and these conditions, its nature still remain controversial, the data available are frequently conflicting and furthermore the direct association between symptoms and reflux is often difficult to establish. For this reason, the majority of clinicians still treat extraesophageal manifestations of GER empirically as esophageal pH testing is not routinely used in the ear, nose and throat (ENT) practice. Purpose of this paper is to examine the relationship between GER and these conditions both in adults and children, through a PubMed database systematic review.