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MINERVA GASTROENTEROLOGICA E DIETOLOGICA
A Journal on Gastroenterology, Nutrition and Dietetics
Indexed/Abstracted in: CAB, EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index
Minerva Gastroenterologica e Dietologica 1999 June;45(2):95-106
language: English, Italian
Impact on the quality of remaining life of treatment with self-expandable metal protheses in patients with inoperable esophago-cardial cancer. Results of a study of 107 consecutive patients treated with ultraflex-type prostheses
De Palma G. D., Siciliano S., Sivero L., Galloro G., Donisi M., Catanzano C.
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Background. Self-expanding metal stents are a new alternative for palliation of esophagocardial malignancies. We evaluated the impact of these stents on the quality of remaining life in patients affected by inoperable esophago-cardial cancer.
Methods. Between September 1992 and September 1997, 102 patients underwent im-plantation of self expanding metal stents for palliation of dysphagia due to esophagene or cardial cancer (76 patients), or for locally recurrent carcinoma after surgery (14 patients), lasertherapy (13 patients) or radiotherapy (5 patients). Stents were implanted under radiological and endoscopic control in patients under mild sedation.
Results. Successful stent implantation was achieved in 102/107 patients (95.3%). Early complications were observed in 4.9% and per-operative mortality was 1.96%. After stent implantation the dysphagia score improved from 3.0, on average, to 0.5, on average. Late complications were evidenced in 25.5%. Weight gain was evidenced in 24.5% and the performance status improved in 14.3%. The mean survival time was 6.9 months.
Conclusions. Self expanding metal stents are an effective alternative for palliation of malignant dysphagia due to esophageal and cardial cancers.