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A Journal on Physical Medicine and Rehabilitation after Pathological Events

Official Journal of the Italian Society of Physical and Rehabilitation Medicine (SIMFER), European Society of Physical and Rehabilitation Medicine (ESPRM), European Union of Medical Specialists - Physical and Rehabilitation Medicine Section (UEMS-PRM), Mediterranean Forum of Physical and Rehabilitation Medicine (MFPRM), Hellenic Society of Physical and Rehabilitation Medicine (EEFIAP)
In association with International Society of Physical and Rehabilitation Medicine (ISPRM)
Indexed/Abstracted in: CINAHL, Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Europa Medicophysica 2005 June;41(2):125-30

language: English

Prognostic value of motor evoked potentials in stroke motor outcome

Nascimbeni A. 1, Gaffuri A. 1, Granella L. 1, Colli M. 2, Imazio P. 2

1 Rehabilitation Unit S. Croce Hospital, Moncalieri, Turin, Italy
2 School of Physical Medicine and Rehabilitation, Turin, Italy


Functional ­study tech­nol­o­gies of the cen­tral ner­vous ­system (CNS) are ­fast devel­op­ing, yield­ing fur­ther objec­tive ­data for evi­dence ­based neu­ro­log­i­cal reha­bil­i­ta­tion. Transcranial mag­net­ic stim­u­la­tion is a ­safe and non inva­sive tech­nique of func­tion­al inves­ti­ga­tion of sev­er­al ­aspects of the CNS. During the ­past few ­years ­many stud­ies ­have ­focused on ­motor ­evoked poten­tials (MEPs) in the inves­ti­ga­tion of cen­tral ner­vous ­system and par­tic­u­lar­ly of cen­tral ­motor path­ways. Among the var­i­ous ­issues of reha­bil­i­ta­tive con­cern in ­this con­text, the prog­nos­tic val­ue of MEPs of ­motor out­come ­after ­stroke is the ­most inter­est­ing one. The aim of ­this ­review, con­duct­ed on Medline data­base, is to ­find out the cur­rent agree­ment in the lit­er­a­ture ­about ­this top­ic and to out­line clin­i­cal cri­te­ria of use of the ­test. Many of the ­retrieved papers ­sug­gest an add­ed val­ue of MEPs on ­motor prog­no­sis ­after ­first ischem­ic syl­vian ­stroke, high­light­ing high­er spec­i­fic­ity in clin­i­cal cas­es ­with par­al­y­sis or ­severe pare­sis in the ­acute ­stage. A clin­i­cal use of MEPs in spe­cif­ic ­stroke sub­groups ­might ­help to ­plan a ­more indi­vid­u­al reha­bil­i­ta­tive pro­ject ­through realis­tic ­motor recov­ery ­goals and select­ed tech­niques of treat­ment; a ­more reli­able ­motor prog­no­sis may ­also be use­ful for reha­bil­i­ta­tion effec­tive­ness ­research and for a ­more ­aimed use of resourc­es.

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