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Istituto San Gallicano, Roma, Italia
Like all malignant cutaneous tumors, melanoma has always represented a difficult challenge for doctors, and especially for dermatologists. In the last few years, in particular, this disease has been the focus of new research and discoveries. For this reason, it seemed interesting to discuss in details the history of melanoma, starting from the early days of humanity up to the present time. In this paper, we discuss some of the major key players and the most significant steps in the evolution and knowledge of this disease. In conclusion, we can say that, unfortunately, history and current events equally prove that melanoma is still a big issue, both from a medical and from a socio-political point of view.