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Puca R. V., Romano F.
Unità Operativa Complessa di Clinica Dermatologica, Seconda Università degli Studi di Napoli, Napoli, Italia
AIM: Acne is characterized by primary lesions localized on the face, chest and back. Such lesions are non-inflammatory (open and closed comedones), or inflammatory (papules and pustules). The inflammatory manifestations are due to Propionibacterium acnes colonization and they can develop into nodules and cysts. Acne may cause important psychological morbidity in affected patients, so a valid therapy should be started as soon as possible to prevent that mild and moderate forms may become severe.
METHODS: In this study 57 Caucasian patients (25 males and 32 females) with mild and moderate acne were treated with Alusac® (Avantgarde, Pomezia, Italy), a multicomponent cream with an innovative formulation (microsilver BGTM, alukina®, zinc gluconate, vitamin B5, echinacea). The patients with moderate acne was also compared with another group of subjects, with moderate acne, treated with Alusac® and topical antibiotic. Acne severity and treatment efficacy were evaluated by means of the Global Acne Grading System (GAGS). Tolerability was also evaluated with specific questionnaires.
RESULTS AND CONCLUSIONS: The results showed that Alusac® is an effective and well-tolerated monotherapy in mild acne, and a valid option in association with topical antibiotic in moderate form.