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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2015 September;17(3):103-10

language: English, Italian

Advanced basal cell carcinoma: how far can surgery get?

Tomassini G. M. 1, Tramontana M. 1, Simonetti S. 1, Cenci N. 2, Stingeni L. 1

1 Sezione di Dermatologia Clinica, Allergologica e Venereologica, Dipartimento di Medicina, Università di Perugia, Perugia, Italia;
2 Unità di Neurochirurgia, Dipartimento di Chirurgia, Ospedale Santa Maria della Misericordia, Perugia, Italia


Basal cell carcinoma represents the most common human malignancy, accounting 80% of non-melanoma skin cancer (NMSK). The term “locally advanced” indicated the forms infiltrating the surrounding tissues, such as muscle, cartilage and bone. We report a case of 74-year-old man with a recurrence of a basal cell carcinoma of the right frontal region infiltrating the underlying bone tissue. The authors describe the surgical technique, with a focus on the multidisciplinary approach of the case and critically evaluating the possibilities offered by surgical treatment, its limits and the risk/benefit ratio in the new “era Vismodegib”.

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