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A Journal on Dermatology
Esperienze Dermatologiche 2015 June;17(2):61-2
Fusidic acid versus botulinum toxin in the treatment of pitted keratolysis: a case report
Miglino B., Tiberio R., Ferri S., Colombo E.
Department of Dermatology, “Maggiore della Carità” Hospital, “A. Avogadro” Piemonte Orientale University, Novara, Italy
Pitted keratolysis is an acquired, chronic disease confined to the stratum corneum of the soles, characterized by multifocal, superficial crateriform pits and superficial erosions. Patients affected by pitted keratolysis frequently complain of plantar hyperhidrosis. We report a patient with pitted keratolysis treated with fusidic acid and botulinum toxin. The response to the treatment was excellent with botulinum toxin treatment. Patient had the plantar keratolysis healing. In conclusion, the hyperhidrosis may be considered the major etiologic factor for pitted keratolysis that does not respond to topic treatment.