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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2015 March;17(1):19-21

language: English

Evaluation of a novel nutraceutical integrator for treatment of mild-to-moderate psoriasis: a pilot study

Fabrizi G., Brognoli D., Pagliarello C., Boccaletti V., Di Nuzzo S.

Section of Dermatology, Department of Clinical and Experimental Medicine, Parma Medical School, Parma, Italy


AIM: Psoriasis is a chronic skin disease with a strong negative impact on quality of life. Diet and nutrients can play a role in the overall therapeutic approach of psoriasis. We conducted a pilot prospective study to evaluate the efficacy of 2-month intake of a food integrator in reducing Psoriasis Area Severity Index (PASI), Body Mass Index (BMI) as well as reducing fasting glucose, cholesterol and triglycerides levels.
METHODS: Twenty consecutive patients affected from mild psoriasis (PASI<10) from Parma outpatient clinic were assigned to treatment with topical calcipotriol alone or with topical calcipotriol plus nutritional supplement if reporting abnormal fasting levels of glucose, cholesterol or triglycerides. PASI, BMI as well as fasting glucose, cholesterol and triglycerides levels were recorded baseline and after two months.
RESULTS: Both groups showed a little but statistical significative PASI improvement. Nutritional supplement significantly improved BMI.
CONCLUSION: Nutritional supplement has the potential to improve metabolic comorbidities of psoriatic patients. Further studies are required.

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