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Home > Journals > Esperienze Dermatologiche > Past Issues > Esperienze Dermatologiche 2014 December;16(4) > Esperienze Dermatologiche 2014 December;16(4):173-8

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CURRENT ISSUEESPERIENZE DERMATOLOGICHE

A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus

Frequency: Quarterly

ISSN 1128-9155

 

Esperienze Dermatologiche 2014 December;16(4):173-8

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Cutaneous hyperpigmentation: solar lentigo as a model of altered interplay between dermis and epidermis

Kovacs D., Cardinali G., Picardo M.

Istituto Dermatologico San Gallicano, IRCCS, Roma, Italia

Several evidences highlighted the key role of the interaction between dermal and epidermal compartments in the regulation of cutaneous pigmentation through the release of mediators involved in the control of melanocyte functionality. An altered synthesis and/or secretion of these mediators may favor the onset of pigmented lesions, e.g. solar lentigo. To extend the knowledge of the complex interplay between the different cell populations in the control of skin pigmentation will allow to develop new therapeutic approaches for the treatment of hyperpigmented lesions.

language: English, Italian


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