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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
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Esperienze Dermatologiche 2014 June;16(2):99-105

language: Italian

Evaluation of the efficacy of two different therapies in the treatment of cutaneous and ocular lesions of rosacea

Roberti V. 1, Lopez T. 2, Coppola R. 2, Zanframundo S. 2, Graziano A. 2, Devirgiliis V. 2, Panasiti V. 2

1 Dipartimento di Dermatologia, Università “Sapienza”, Roma;
2 Unità di Chirurgia Ricostruttiva, Università “Campus Bio-Medico”, Roma


Rosacea is a common disease affecting about 3% of world population, most of all women aged between 30 and 50 years. The most frequent cutaneous features are erythema, teleangectasia, papular and pustular lesions. Eyes are frequently involved, displaying lacrimation, photophobia, burning and foreign body sensation. Currently the treatment of rosacea is based on different pharmacological schemes with single or associated drugs, administered topically or systemically. In this paper we evaluated the efficacy of two different drugs usually used in the treatment of rosacea (topical metronidazole and systemic doxycycline), associated with a topical ophthalmic antibiotic to treat the ocular symptoms of rosacea. Both therapeutical schemes were safe and effective, without any statistical differences.

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