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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2013 June;15(2):71-3

language: English

A case report of a rare dermatosis: perforating granuloma annulare

Patrizi A., Venturi M., Pazzaglia M., Misciali C., Neri I.

Department of Specialized, Experimental and Diagnostic Medicine, Division of Dermatology, University of Bologna, S. Orsola- Malpighi Hospital, Bologna, Italy


We report the case of an 84-year-old male patient with 5 lesions on the dorsum of his hands, diagnosed as perforating granuloma annulare (PGA). It is an uncommon dermatosis that even more rarely occurs in elderly age in association with type II diabetes mellitus, as in our patient. In our case PGA spontaneously regressed just with an emollient cream; in fact, granuloma annulare self-limits within two months to two years in more than 50% of cases. Anyway, therapies including moderate potency topical steroids under occlusion, intralesional steroid injections, tacrolimus ointment, pimecrolimus cream, imiquimod, and cryotherapy are reported in limited form of PGA.

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