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Farinelli P. 1, Gironi L. C. 1, Astolfi S. 1, Bellinzona F. 1, Delrosso G. 1, Valente G. 2, Colombo E. 1
1 Clinica Dermatologica, Azienda Ospedaliero-Universitaria Maggiore della Carità, Novara;
2 Servizio di Anatomia Patologica, Azienda Ospedaliero-Universitaria Maggiore della Carità, Novara
Acquired perforating dermatoses (APD) are a group of dermatologic diseases that affect especially adult patients with diabetes mellitus and/or chronic renal failure. They are characterized by umbelicate itchy papules typically arisen on scratching areas. Clinical differential diagnosis includes: prurigo nodularis, pityriasis lichenoides, perforating granuloma annulare. Transepidermal elimination of dermal material represent the pathognomonic histological feature. Authors present the case of a 64-year-old Caucasian male patient, affected by chronic renal failure, who presented diffuse pruritic papules distributed on the lower limbs. Histological exam of one lesion led to diagnosis of APD.