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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2011 June;13(2):91-4


language: English, Italian

Clinical evaluation of recovery and anti-inflammation efficacy of a moisturizing topical product in hand eczema

D’Erme Massimiliano A. 1, Milanesi N. 1, Simonacci F. 2, Lotti T. 1, Gola M. 1

1 Clinica Dermatologica, Dipartimento di Area Critica Medico-Chirurgica, Università di Firenze, Firenze, Italia 2 Univesità degli Studi di Ancona, Ancona, Italia


Aim. Hands may be affected by several pathological conditions such as atopic dermatitis, allergic or irritant contact dermatitis, dysidrosis etc. The initial phase of hand eczema can be treated with emollients, specifically formulated to restore a damaged physiological condition. In fact, the improvement of skin barrier is essential for maintaining skin integrity and reducing trans-epidermal water loss (TEWL). The aim of our work was the study of efficacy of an emollient, containing a special mixture of substances such as glycerol, serine, polysaccharide, alginates, etc., without preservatives and fragrances, that acting on the osmotic pressure, hold water on the skin surface, forming a three-dimensional structure that can moisturize and protect hands skin.
Methods. We examined the efficacy of the emollient in a group of 16 patients suffering from hand dermatitis, analyzing the impact on various clinical features of eczema during one month of treatment.
Results. The product we used, has demonstrated a good efficacy to decrease hand dermatitis clinical signs.
Conclusion. In conclusion, the specific composition of the product and the efficacy observed, advise us to use this emollient either for patients with mild hand dermatitis or as valid therapeutic support for moderate and severe hand dermatitis.

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