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ESPERIENZE DERMATOLOGICHE

A Journal on Dermatology


Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
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Esperienze Dermatologiche 2011 June;13(2):65-7

language: English, Italian

Plaque morphea in a patient with primary biliary cirrhosis

Berruti V. 1, Zanchini R. 1, Colasanti P. 1, Cordedda M. 1, Picciotti E. 2, Mozzillo R. 1

1 Unità Operativa di Dermatologia e Venereologia, Ospedale San Gennaro dei Poveri - ASL1, Napoli, Italia
2 Unità Operativa di Anatomia Patologica, Ospedale Pellegrini - ASL1, Napoli, Italia


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Scleroderma is a chronic disease of unknown origin and characterized by cutaneous fibrosis. Two clinical entities are distinguished: localized scleroderma involving only the skin, with possible spread to the underlying muscuoloskeletal tissues; and systemic scleroderma, with a poorer prognosis and involvement of internal organs. Here we report the case of a 58-year-old woman with a 10-year history of primary biliary cirrhosis and a four-year history of infiltrated scleroatrophic plaques. Histologic examination of a lesion biopsy was diagnostic for localized scleroderma.

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