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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2010 September;12(3):145-50

language: English, Italian

Melanocytic nevi: management by evidence-based medicine

Lo Scocco G., Fabroni C., Salvini C.

Unità Operativa di Dermatologia, Azienda USL 4 di Prato, Prato,Italy


Melanoma is a malignant tumor that arises from melanocytes. This cell, responsible for the synthesis of melanin is present in the skin, mucous membranes and particularly in nevus. The relationship between nevi and melanoma is complex and still not entirely clear. There is a statistically significant correlation between number of melanocytic nevi and melanoma risk. In particular it was noted that the occurrence of clinically atypical nevi is associated with an increased risk of melanoma. The management of patients with melanocytic pigmented lesions is therefore essential in the prevention of melanoma. In this article we will examine, through a review of international literature, some critical issues facing the specialist dermatologist in his clinical practice to improve its ability to diagnose melanomas in an increasingly early stage of development.

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