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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2010 June;12(2):73-7

language: English, Italian

Subacute cutaneous lupus erythematosus

Pini M., Balice Y., Crippa D.

Unità Operativa Struttura Complessa di Dermatologia, Azienda Ospedaliera San Gerardo, Monza, Italia


Subacute cutaneous lupus erythematosus (SCLE) is a cutaneous eruption that manifests itself with reddish-purple psoriasi-like patches in a reticulate pattern or with polymorphous eruptions that progress to annular scaly patches with an erthematous border often coalescing into polycyclic areas. Fine angiectases are consistently seen. No atrophy is observed. The lesions usually arise on the shoulders, the upper back, the extensor aspect of the arms, the dorsi of the hands; erythematous angiectases are often seen on the face. Exposure to sunlight is a frequent precipitating factor in alternating episodes of exacerbation and quiescence. Standard therapy is with corticosteroids and antimalarials. Adjuvant therapy includes administration of dapsone, thalidomide, retinoids, interferon, and immunosuppressants. We present the case of a 76-year-old man with erythematous-edematous lesions on the sun-exposed skin of the head and neck and scaly papules on the trunk and upper extremities. Hydrochloroquinine (400 mg/die) therapy resolved the skin picture.

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