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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2010 June;12(2):69-72

language: English, Italian

Lupus miliaris disseminatus faciei resolved with photodynamic therapy

Burtica C., Ismaili A., Fanti P. A., Bardazzi F.

Dipartimento di Medicina Interna, dell’Invecchiamento e Malattie Nefrologiche, Sezione di Clinica Dermatologica, Università di Bologna, Bologna, Italia


Lupus miliaris disseminatus faciei (LMDF), or acne agminata, is a rare disorder of rapid onset that manifests clinically with a variable number of small reddish-brown papules; its histological features include epithelioid cells and caseous or non-caseous granulomas in the derma. Its origin remains unknown. Some authors believe LDMF to be a distinct entity, whereas others consider it a variant of granulomatous rosacea. The mainstay of treatment is with tetracycline, although non-response to tetracycline therapy has been reported. Recent studies have described treatment with isotretinoin in which symptoms recurred after retinoid therapy was suspended. We present the case of a 19-year-old man with LMDF which resolved with photodynamic therapy.

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