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ESPERIENZE DERMATOLOGICHE

A Journal on Dermatology


Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
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Esperienze Dermatologiche 2009 March;11(1):7-10

Copyright © 2009 EDIZIONI MINERVA MEDICA

language: English, Italian

Unusual clinical presentation of Dowling-Degos disease

Panetta C., Donati P., Cota C., Muscardin L., Amantea A.

Serivizio di Dermatopatologia, Istituto Dermatologico San Gallicano, IRCCS – Roma


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This case report describes an unusual presentation in a 41-year-old woman of Dowling-Degos disease associated with acne conglobata. Physical examination revealed hyperpigmented coalescent patches in the skin folds and nodules and abscesses resembling acne conglobata in the axillae. Histology of a hyperpigmented patch demonstrated a characteristic feature of Dowling-Degos disease: hyperplasia of prolonged and anastomized epidermal ridges in a reticulate pattern associated with increased melanic pigment of the basal layer and pseudocysts. The rare copresentation of these conditions suggest a follicular proliferation defect that could predispose to the formation of occlusive acneiform lesions.

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