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A Journal on Dermatology

Journal of Istituto Dermatologico San Gallicano
Official Journal of the Associazione Dermatologi Ospedalieri Italiani - A.D.O.I.
Indexed/Abstracted in: EMBASE, Scopus



Esperienze Dermatologiche 2008 December;10(4):169-73

language: English, Italian

Human granulocytic anaplasmosis presenting with a widespread petechial exanthema in a 9-year-old boy

Brunasso A. M. G. 1,2, Massone C. 2

1 Dipartimento di Dermatologia, Ospedale Galliera, Genova, Italia
2 Dipartimento di Dermatologia, Università di Graz, Graz, Austria


Human granulocytic anaplasmosis (HGA) is an emerging disease, described for the first time in 1994. It occurs during spring and summer months in the upper Midwestern and Northeastern regions of the United States, and in central and eastearn Europe as well. The causative pathogen is the Anaplasma phagocytophilum, a vector-born and an obligate intracellular pathogen transmitted by Ixodes spp, that belongs to the Rickettsiacae family. Cutaneous manifestation of HGA are unusual and they have been reported in different studies with a frequency of 1-16%. This article describes the case of a 9-year-old boy with HGA, who presented with a disseminated purpuric rash and fever. Skin manifestations in HGA are rare and not clearly reported in the Literature. Dermatologists should be aware of HGA in the differential diagnosis of patients presenting with skin rashes and fever.

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