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CURRENT ISSUEGIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
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Giornale Italiano di Dermatologia e Venereologia 2016 Nov 15

Prognostic role of histological regression in cutaneous melanoma

Simone RIBERO 1, 2, Simona OSELLA-ABATE 3, Emi DIKA 4, Eugenio SPORTOLETTI BADUEL 2, Elena MARRA 1, Franco PICCIOTTO 2 , Virginia CALIENDO 2 , Maria T. FIERRO 1, Pietro QUAGLINO 1

1 Department of Medical Sciences, Section of Dermatology, University of Turin, Turin, Italy; 2 Department of Oncology, Section of Dermatologic Surgery, University Hospital “Città della Salute e della Scienza di Torino, Turin, Italy; 3 Department of Medical Sciences, Section of Surgical Pathology, University of Turin, Turin, Italy; 4 Unit of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy

Histological regression in primary cutaneous melanoma occurs in 10-35% of cases. Although there is a large body of literature on histological regression and prognosis in melanoma patients, not clear data concerning this feature has been reported. In the current review, a comprehensive overview of the main aspects of regression will be provided. The clinical utility of regression as a prognostic factor has been challenged recently. Nowadays evidences reported that this feature is protective on SLN metastases. Despite its association with poor prognostic factors, it maintained a favourable prognostic role in many different survival studies.

language: English


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