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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Benedetta MIGLINO 1, Michele VIANA 2, Rossana TIBERIO 1, Paolo BOGGIO 1, Guido VALENTE 4, Gionata STRIGARO 3, Enrico COLOMBO 1
1 Dermatologic Clinic “Maggiore della Carità” Hospital and UPO-University of Eastern Piedmont, Novara, Italy; 2 Headache Science Center, C. Mondino National Neurological Institute, Pavia, Italy; 3 Neurological Department “Maggiore della Carità” Hospital and UPO-University of Eastern Piedmont, Novara, Italy; 4 Pathology Department, “Maggiore della Carità” Hospital and UPO-University of Eastern Piedmont, Novara, Italy
The authors report a case of sensorimotor polyneuropathy, diffuse hemangiomas and monoclonal gammopathy. Besides weight loss, there were diabetes mellitus and severe hypothyroidism. These alterations were consistent with POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy and Skin changes) syndrome, which is a rare systemic disease with monoclonal proliferation of plasmacytes and slow progression. Because of its rarity, the incidence of this disease is still unknown.