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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Valentina DINI 1, Patrizia MARTINI 2, Mauro BELLINI 3, Giovanni BAGNONI 4, Franco MARSILI 5, Ugo LANCIA 6
1 Department of Dermatology, University of Pisa, Pisa, Italy; 2 Unit of Dermatology, Hospital of Lucca, Lucca, Italy; 3 Hospital of Massa, Italy; 4 UOC Dermatology Director, Az USL 6, Livorno, Italy; 5 Hospital of Versilia, Viareggio, Italy; 6 University of Rome ”Tor Vergata”, Department of Biology, Roma, Italy
BACKGROUND: Psoriasis arthritis will develop during cutaneous psoriasis in a significant percentage. The aim of this study was to improve assistance to patients and to provide the most individualized care possible.
METHODS: Patients: all consecutive subjects with psoriasis accessing the outpatients facilities of five dermatologic centres of excellence in the Tuscany region of Italy between December 2014 and February 2015. All subjects were screened for the presence of a previous diagnosis of arthritis and symptoms affecting the articular system, using some questions chosen and shared by dermatologists in charge of the centers.
RESULTS: In the chosen three months period, 134 patients affected with psoriasis had been observed, 32 (24 %) of which answered “yes” to the question “Have you ever been diagnosed with arthritis?”. There have been differences in the characteristics of patients in the two groups, with and without arthritis. In particular, in the arthritis patients a statistically significant higher mean age, more ungueal psoriasis, less body surface cutaneous psoriasis extension, and a statistically significant higher percentage of patients treated with biological drugs (57 % vs. 24.5 %) have been observed.
CONCLUSIONS: The results were consistent with the scientific literature in the field. The experience seems to confirm the opportunity of screening programs on arthropathy in cutaneous psoriasis patients. About a quarter of psoriasis patients had relevant arthropathic features, and more than half of these required challenging therapies like biologics.