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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Ponzetti A. 1, Ribero S. 2, Caliendo V. 2, Spadi R. 1, Macripò G. 2, Lista P. 1
1 Medical Oncology 1 Division, Department of Hematology and Oncology, “Città della Scienza e della Salute”, San Giovanni Battista Hospital, Turin, Italy;
2 Dermatologic Surgery Unit, Department of Hematology and Oncology, “Città della Scienza e della Salute”, San Giovanni Battista Hospital, Turin, Italy
Eccrine porocarcinoma is a rare and aggressive skin neoplasm; only two cases of sarcomatous differentiation have been reported. Whereas surgery is effective as first line treatment, optimal management of recurrent or metastatic porocarcinoma is not defined and needs multidisciplinary approach.
Here we described the first reported case of metastatic sarcomatoid porocarcinoma. Our patient experienced multiple recurrences, mainly loco-regional, and was treated with a multidisciplinary treatment, involving surgery, radiotherapy, chemotherapy and target therapy, leading to a more than 4 years survival, from the first recurrence.
We conclude that multidisciplinary approach in metastatic porocarcinoma must involve surgeon, radiotherapist and medical oncologist. The combination of local and systemic treatments can delay recurrence and prolong survival also in very aggressive cases.