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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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  PANNICULITIDES: THE SPECTRUM OF THEIR DIAGNOSES AND DIFFERENTIAL DIAGNOSES


Giornale Italiano di Dermatologia e Venereologia 2013 August;148(4):371-85

Copyright © 2013 EDIZIONI MINERVA MEDICA

language: English

Panniculitis in children

Grassi S. 1, Borroni R. G. 2, Brazzelli V. 1

1 Dipartimento di Scienze Clinico-Chirurgiche Diagnostiche e Pediatriche, Sezione di Dermatologia Università di Pavia, Fondazione IRCCS Policlinico “San Matteo”, Pavia, Italia; 2 Laboratori Sperimentali di Ricerca - Area Trapiantologica Fondazione IRCCS Policlinico “San Matteo” Pavia, Italia


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This paper will give a comprehensive view of the most frequent panniculitides seen in childhood, with emphasis on the types exclusively found in infancy, and for all other types of panniculitides also found in adults. Aim of this paper is also to analyze the clinical differences between panniculitis in childhood and in adulthood, and to give reliable histopathologic criteria for a specific diagnosis. A review of the literature is here integrated by authors’ personal contribution. Panniculitides in children is a heterogeneous group of diseases, as well as in adult life, characterized by inflammation of the subcutaneous fat. Only very few types of panniculitis are exclusively found in childhood, such as Sclerema neonatorum and subcutaneous fat necrosis of the newborn, while the vast majority of the other types may be found both in paediatric age and in adults. Furthermore, this paper will consider in detail panniculitis according to their frequency, such as Erythema nodosum, Lupus panniculitis, Cold panniculitis, panniculitis in Behçet disease, and poststeroid panniculitis. It will also describe rare forms of panniculitis, such as Eosinophilic panniculitis (a pathological entity debated by many authors), Subcutaneous panniculitis T-cell lymphoma, and the different forms of the so call “Lipophagic panniculitis”, encompassing respectively the febrile relapsing panniculitis of Weber-Christian disease and the non-relapsing form of Rothmann-Makai disease. For each type of panniculitis considered concise information will be given about epidemiology, etiology, clinical findings, laboratory data, prognosis and therapy, while histopathologic findings will be described in detail.

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sara.grassi03@gmail.com