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A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2012 December;147(6):637-47

language: English

Vitiligo: recent insights and new therapeutic approaches

Lotti T. M. 1, Berti S. F. 2, Hercogova J. 3, Huggins R. H. 4, Lee B. W. 4, Janniger C. K. 4, Schwartz R. A. 4

1 Dermatology and Venereology, University “G. Marconi”, Rome, Italy;
2 Pediatric Dermatology, A. Mayer Hospital, Florence, Italy;
3 Department of Dermatology, 2nd Medical Faculty, C harles University, Prague, Czech Republic;
4 Dermatology and Pediatrics, New Jersey Medical School, Newark, NJ, USA


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Vitiligo represents a selective destruction of the melanocytes. It is a relatively common, probably autoimmune disorder that affects people of all backgrounds and both genders. No particular group seems to be preferentially affected. Half of vitiligo patients have an onset before the age of 18 years. In regions where leprosy is endemic, individuals with vitiligo are often stigmatized due to similarities in appearance between the two diseases. We will review this important subject, emphasizing the latest therapeutic advances.

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