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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2012 February;147(1):91-7
Evaluation of incidental thyroid nodules in patients with primary melanoma
Fanti P. A. 1, Dika E. 1, Balestri R. 1, Rech G. 1, Bellavista S. 1, Baldi E. 2, Maibach H. I. 3, Patrizi A. 1 ✉
1 Division of Dermatology, Department of Internal Medicine Geriatric Diseases and Nephrology, University of Bologna, Bologna, Italy;
2 Department of Medicine and Public Health, University of Bologna, Bologna, Italy;
3 Department of Dermatology, University of California, School of Medicine, San Francisco, CA, USA
AIM: Literature data have suggested an increase of incidental thyroid nodules in patients with malignancies, including melanoma.
METHODS:The ultrasound findings of 168 consecutive melanoma patients were revisited in order to evaluate the presence of incidental thyroid nodules and the results were compared with clinical features, Breslow thickness and the rate of malignancy of incidental thyroid nodules.
RESULTS:We observed that: 1) incidental thyroid nodules are more frequent in patients affected by melanoma (60.6%) than in the healthy population; 2) no statistically significant difference were found in thyroid involvement on the basis of gender and age; 3) incidental thyroid nodules frequency is increased in patients with thinner melanoma and this increase is more evident if we consider melanoma in situ and female patients; 4) it was not detected malignant incidental thyroid nodules.
CONCLUSION:The data revealed a high frequency of incidental thyroid nodules in patients with melanoma, suggesting that it is necessary to study this association in a larger group of patients, also including age/gender matched controls.