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Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Online ISSN 1827-1820
Betti R. 1, Crosti C. 2, Moneghini L. 3, Ghiozzi S. 1, Crespi E. 1, Radaelli G. 4, Menni S. 1
1 Dermatological Clinic, San Paolo Hospital, University of Milan, Milan, Italy;
2 Department of Anesthesia, Intensive Care and Dermatological Sciences, Università degli Studi di Milano Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy;
3 Department of Medicine, Surgery and Dentistry, Division of Pathology, University of Milan;
San Paolo Hospital and Fondazione IRCCS Ca’ Granda, Maggiore Policlinico Hospital, Milan, Italy;
4 Unit of Medical Statistics, San Paolo Hospital, University of Milan, Milan, Italy
AIM: Spindle and/or epithelioid cells nevi represent the spectrum of a clinico-pathologic entity with different characteristics. Aim of the study is to provide information about the differences in characteristics of these nevi for different groups of age.
METHODS: Two different groups are considered: younger than 15 years and older than 15 years. An analysis of 187 spindle and/or epithelioid cells nevi was performed. Forty-five pediatric patients (24 males and 21 females) and 142 adult patients (44 males and 98 females) were examined. Age, sex, type of nevus, location, clinical characteristics were evaluated.
RESULTS: Spindle and epithelioid cells nevi were observed in 53% of the pediatric and in 45% of adult patients. Female more frequently presented with spindle nevus cell both in pediatric (56%) and in adult (70%) cases. In pediatric patients, the anatomical distribution was prevalent in the areas of the head and neck. Pigmentation was not a distinctive feature of pediatric cases and only interested the spindle and epithelioid cells nevi. The regularity of borders was not a distinctive character for neither of the groups of patients. Uniformity in color occurred more frequently in pediatric patients.
CONCLUSION: Spindle and/or epithelioid nevi belong to the same spectrum of pathologies, they behave differently in the different groups of age thus permitting a certain degree of clinical distinction in different age groups.