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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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  OPTIMIZING MANAGEMENT ON NON-MELANOMA SKIN CANCERS


Giornale Italiano di Dermatologia e Venereologia 2009 August;144(4):433-9

language: English

Optimizing ALA-PDT in the management of non-melanoma skin cancer by fractionated illumination

De Vijlder H. C. 1, Middelburg T. 1, De Bruijn H. S. 2, Martino Neumann H. A. 1, Sterenborg H. C. J. M. 2, Robinson D. J. 1,2, De Haas E. R. M. 1

1 Department of Dermatology, Erasmus MC University Hospital, Rotterdam, The Netherlands
2 Centre of Optical Diagnotics and Therapy (CODT), Department of Radiation Therapy, Erasmus MC University Hospital, Rotterdam, The Netherlands


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The aim of this review was to describe briefly the mechanism and history of photodynamic therapy (PDT). The achieved preclinical and clinical results in Rotterdam are discussed in the light of a search to optimize aminolevulinic acid-photodynamic therapy (ALA-PDT). As the incidence of skin cancer is rising, an optimized treatment in non-melanoma skin cancer is needed.

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