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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2008 April;143(2):161-5

language: English

Randomized prospective study on the efficacy of a new revitalizing filler composed of hyaluronic acid (Wipeline®)

Dessy L. A., Trignano E., Scuderi N.

Department of Cutaneous and Venereal Diseases and Plastic Surgery “La Sapienza” University of Rome, Rome, Italy


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Aim. The aim of the study was to test the efficacy of a new revitalizing filler (Wipeline®) formed by a buffer physiological solution of hyaluronic acid (HA).
Methods. A prospective study was performed on 100 patients (aging between 40 and 70 years), with clear signs of premature facial aging. Patients were randomly assigned to two groups, one treated with a HA concentration of 1.6%, the other with a concentration of 2% in the tested product. The treatment protocol consisted of three sessions with a four weeks intervals between them. Visual Analogue Scale (VAS) and digital photos were used to evaluate results after 1, 3, 6 and 12 months from treatment end.
Results. An improvement of turgidity, elasticity and luminosity of the skin and a reduction of folds and wrinkles of the treated areas were observed in both groups. The higher concentrated solution of HA had a more prolonged effect and a greater filling effect. Products were well tolerated and no adverse reactions observed.
Conclusion. The efficacy of Wipeline® has been clinically supported. This revitalizing filler succeeded in increasing skin elasticity and tone by dermal hydration. The procedure is simple and little invasive. It represents a good treatment option to restore vitality and turgidity of skin presenting the signs of aging.

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