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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA
A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
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Giornale Italiano di Dermatologia e Venereologia 2007 December;142(6):699-702
Skin manifestations associated with Rotavirus infections
Di Lernia V., Guareschi E.
Department of Dermatology Arcispedale Santa Maria Nuova Reggio Emilia Hospital Reggio Emilia, Italy
Rotaviruses are important etiological agents of nosocomial infections in childhood and are the main pathogens of infantile diarrhea which is still associated with high mortality in developing countries and morbidity. Although a specific dermatologic clinical picture is not associated to these infections, different clinical manifestations, which include maculo-papular exanthema, Gianotti-Crosti syndrome, and acute infantile hemorrhagic edema, have been reported in course of rotavirus infections. The prognosis is excellent in healthy, immunocompetent individuals even if a possible involvement of rotavirus in the pathogenesis of celiac disease has been postulated. To prevent rotavirus infections a pentavalent vaccine was recently licensed by the US Food and Drug Administration.