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GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA

A Journal on Dermatology and Sexually Transmitted Diseases


Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
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Giornale Italiano di Dermatologia e Venereologia 2006 August;141(4):409-14

language: English

Phytoestrogens in dermatocosmetology. Clinical and instrumental trial conducted on a cream made from glicine and other bioflavonoids in spontaneous menopausal women

Giorgini S. 1, Greco A. 1, Cristina Melli M. 2, Lotti T. M. 3

1 Operative Unit of Professional and Environmental Dermatological Allergology University of Florence, Florence, Italy
2 Department of Dermatological Science University of Florence, Florence, Italy
3 Operative Unit of Dermatological Physiotherapy University of Florence, Florence, Italy


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Aim. Previous evidence suggests that skin cosmetics containing titled phytoestrogens have good moisturizing and antifree radical properties. This study sought to confirm these properties in the study product and the advantages linked to its use.
Methods. This open experimental study evaluated a cream containing glycine soja in 17 menopausal women (age range, 48-59 years; mean age, 53.5 years) who had never undergone filler treatment and had not used antiaging creams containing phytoestrogens in the year prior to the start of the trial.
Results. The study product was well tolerated by 90% of the sample. Two women suspended treatment after a few days: one because she did not like the fragrance that had been added to the product at the outset and the other because of a burning sensation and skin reddening on application of the cream.
Conclusion. The results indicate that topical skin products containing phytoestrogens are useful to and appreciated by postmenopausal women. They may be used in treating physiological aging, and photo-aging in particular. No undesired effects were noted; the patch test with c.t. product and the use test produced no adverse reactions.

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