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A Journal on Dermatology and Sexually Transmitted Diseases
Official Journal of the Italian Society of Dermatology and Sexually Transmitted Diseases
Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,014
Giornale Italiano di Dermatologia e Venereologia 2006 February;141(1):63-8
What to do when acne treatments fail?
Stefanaki I., Katsambas A. D.
Department of Dermatology University of Athens, Andreas Sygros Hospital, Athens, Greece
Acne is a very common disease affecting both sexes from adolescence until their 4th decade. This extremely common condition has a major impact on the quality of life of patients, with significant physical, psychological and economical aspects. It is caused by increased sebum production, ductal cornification, bacterial colonization of the pilosebaceus ducts and inflammation. Topical and systemic treatment modalities aim against the various aetiological factors, and maintenance therapy is required in order to avoid relapses. Despite proper management and good patient compliance, there are cases of treatment failures. This article offers an overview of the guidelines on the treatment of acne, and highlights the aetiology and management in cases of poor response.